The Medusa Nebula is a large planetary nebula in the constellation of Gemini on the Canis Minor border. It also known as Abell 21 and Sharpless 2-274. It was originally discovered in 1955 by UCLA astronomer George O. Abell, who classified it as an old planetary nebula.[4] The braided serpentine filaments of glowing gas suggests the serpent hair of Medusa found in ancient Greek mythology.

Until the early 1970s, the Medusa was thought to be a supernova remnant. With the computation of expansion velocities and the thermal character of the radio emission, Soviet astronomers in 1971 concluded that it was most likely a planetary nebula.[4]

As the nebula is so big, its surface brightness is very low, with surface magnitudes of between +15.99 and +25 reported. Because of this most websites recommend at least an 8-inch (200 mm) telescope with an [O III] filter to find this object although probably possible to image with smaller apertures.